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Saturday, September 4, 2010

Selecting medical students : Need for a change

Do the medical entrance tests correctly measure a student's ability to become a good doctor? Research shows otherwise. Here are some excerpts from a recent article published in The Lancet.
'performance in the premedical sciences is inversely associated with many of the personal, non-cognitive qualities so central to the art of medicine.'...
students' undergraduate science grades and MCAT science scores were associated with grades in the first 2 years of medical school, but were, “almost completely unrelated to performance in the fourth year and to faculty rating of general and clinical competence”....
students who did better in science were, “narrower in interests, less adaptable, less articulate, and less comfortable in interpersonal relationships”....
students who were most successful in the sciences, “have an impersonal orientation: they are not very interested in others”. ...
students who did the best in the premedical sciences scored lower on standardised measures of empathy and tended to be “shy”, “submissive”, “withdrawn”, or “awkward and ill at ease socially”, characteristics the author suggested are, “the antithesis of what most of us would want in a clinician”....
In response to growing data that balancing cognitive and non-cognitive strengths of applicants does not compromise eventual medical quality, some medical schools in the UK and USA have either adopted, or are evaluating, alternative admission criteria. A leader in this area has been McMaster Medical School in Canada with its “Multiple Mini Interview” used to assess psychological and personality aspects of potential students. The Humanities and Medicine Program of the Mount Sinai School of Medicine in New York offers another example.
Read more: 'Science as superstition: selecting medical students : The Lancet

Thursday, September 2, 2010

Free online database of ADME, PK, and physicochemical data

Free online database of marketed drugs
ADME, PK, and physicochemical data
Aid your drug discovery and development

Features

Search the database for phys-chem, ADME and PK
properties of marketed drugs

Free online access via www.cloegateway.com
2D and 3D visualisation tools for viewing the relationships between ADME and physicochemical properties
All drugs are classified using the WHO ATC classification index, allowing identification of drugs by therapeutic area
Data compiled from Cyprotex in vitro ADME testing and literature values

SciVerse

Effective August 28, 2010 ScienceDirect, Scopus and the targeted web content from Scirus have been integrated within one platform - SciVerse.
(NB All existing URLs will remain active and there will be no interruption of inward or outward links to your subscribed content.)
Go to www.sciverse.com to access the SciVerse platform.
The home page for SciVerse is the new SciVerse Hub beta from which users can access:
Search results across ScienceDirect, Scopus and scientific web content, ranked by relevance and without duplication
Three free applications that enhance search and discovery, allowing you to:
Search only the methods/experimental procedures sections of the articles in ScienceDirect
See search results in full sentences to help find the right content faster
See a list of the most prolific authors for a given search topic
For more information (including answers to frequently asked questions) about SciVerse and the new releases of ScienceDirect and Scopus, please visit www.info.sciverse.com

Wednesday, September 1, 2010

Why Starved Flies Need Less Sleep - Science News

I was wondering how we can do our normal routine work, even more work, in Ramadhan despite getting less than normal sleep. Also how do saints (buzurgs) cope up with less sleep and do a lot of mental work during the day? Here is the research which points to the answer. Fasting and having less food prevents building up of substances that induce sleep. For details see Why Starved Flies Need Less Sleep - Science News

Monday, August 30, 2010

Novartis receives FDA approval of Tekamlo, a single-pill combination of aliskiren and amlodipine to treat high blood pressure

The US Food and Drug Administration (FDA) approved Tekamlo (aliskiren and amlodipine) tablets, a single-pill for the treatment of high blood pressure combining the only approved direct renin inhibitor, Tekturna (aliskiren), with the widely used calcium channel blocker amlodipine. Since Aliskiren is already in the market, it needs to be seen which one of the 3 classes of drugs tergeting the renin-angiotensin-aldosterone system (angiotensin receptor blockers, ACE inhibitors and renin inhibitors) is a better alternative for hypertensive patients. In our medical school we are initiating a trial comparing newer angiotensin receptor blockers and ACE inhibitors. I do not know whether aliskiren is available in India and at what cost.

Novartis receives FDA approval of Tekamlo, a single-pill combination of aliskiren and amlodipine to treat high blood pressure

Tuesday, August 24, 2010

Development and Validation of a New Prescription Quality Index - Hassan - 2009 - British Journal of Clinical Pharmacology - Wiley Online Library

Prescription Quality Index- A new index to measure quality of prescriptions.
Prescription Quality Index• Many studies raise serious questions about the prescribing appropriateness and prescription quality. However, there is a lack of a single measure which will capture all facets of prescription quality.

• Evaluation of prescriptions was usually based on expert judgement of practitioners.

• Definition of prescription quality, reference model, validity and reliability of the measurement tools, and other data such as the number, type and severity of diagnosis of patients were usually insufficient or lacking.

What this study adds

• The Prescription Quality Index (PQI) was developed with a strong structural foundation and was able to capture the clinical, clerical, and legal requirement of a prescription.

• Extensive psychometric testing was performed on the PQI and the new tool demonstrated acceptable validity and reliability.

• The PQI has been shown to be a valid, reliable and responsive tool to measure quality of prescriptions in chronic diseases.

Development and Validation of a New Prescription Quality Index - Hassan - 2009 - British Journal of Clinical Pharmacology - Wiley Online Library

Free Technology for Teachers: 140 New Things Being Tried In Classrooms This Fall

A google presentation of 142 new tips innovative tech-savvy teachers around the world are trying in their classrooms. If you have any new idea for your classroom, please leave a comment.
Free Technology for Teachers: 140 New Things Being Tried In Classrooms This Fall

Tuesday, August 3, 2010

Career Advice: Do You REALLY Want to Be a Professor? - Inside Higher Ed

Time to slow down and reflect: A must read article for all those who are in an academic career and do not feel very satisfied. Career Advice: Do You REALLY Want to Be a Professor? - Inside Higher Ed

Free Books, powerpoint presentations, teaching tools and resources and drug information