Presurgical Antibiotic Prophylaxis Pattern In An Indian Tertiary Care Teaching Hospital

Authors: Rupinder Kaur, Mohd Tariq Salman, Narendra K. Gupta, Uma Gupta, Ali Ahmad, Vinod K. Verma

The present study was performed to study the antibiotic prophylaxis pattern in patients admitted in Surgery and Obstetrics and Gynaecology wards of a Tertiary Care Teaching hospital in North India. It was an observational, non interventional and analytical study used to evaluate the patients undergoing surgery through period of one and half years. Information concerning demographic data, type of surgery, and parameters of antibiotic therapy (selection of antibiotic, dose, route and duration of therapy as well as cost) was collected from case records of 400 patients. Third generation cephalosporins were the most commonly prescribed class of antibiotics. No consistency was noted in the timing of administration of prophylactic antimicrobials agents which were prescribed 30 minutes to 6 hours before surgery. The dose was not repeated during surgery. Majority of antibiotics were prescribed from Essential Medicines List. Surgical prophylaxis was inappropriate in terms of choice of antimicrobial agent, timing of administration as well as the total duration of prescription, in majority of the cases. Interventions are warranted to promote the development, dissemination and adoption of evidence based guidelines for antimicrobial prophylaxis.

JK Science Vol. 17 No. 2, April - June 2015

Drug Prescribing Pattern in Dental Teaching Hospital

MT Salman, FA Khan, SZ Rahman, M Makhdoom. JK Science, Vol. 11 No. 2. 107, April-June 2009

Objective: To study drug prescribing pattern in the Dental OPD.
Methods: 50 prescriptions were collected from Ziauddin Ahmad Dental College, AMU, Aligarh, and analyzed for percentage of drugs prescribed as per VEN Method. We also looked into the percentage of drugs prescribed with generic name, groups of drugs commonly prescribed, antibiotics’ prescription pattern, number of injections and cost per prescription as per WHO basic drug indicators.
Results: The percentage of drugs from Essential Medicines List (EML) was 25%, while percentage of drugs prescribed by Generic Name was only 4%. Most common groups of drugs prescribed by Dental Physicians were Antiseptics (40%), NSAIDs (34%), Antibiotics (30%) and Vitamins (4%). The most extensively prescribed drug from each group was Betadine Gargle, Tablets Voveron, Novaclox and Basiton Forte respectively. The average number of drugs prescribed, number antibiotics prescribed and cost per day per prescription were 3, 1 and Rs. 24.2 respectively.. Average number of antibiotics prescribed per prescription was 1.0. No injection was prescribed to any patient.
Discussion: After reviewing the above prescriptions, the pattern of drug prescribing is not based on WHO criteria for rational use of drugs. The system is not at all evidence based. It is thus necessary to make physicians of Dental College aware about the use of drugs from EMLs, importance of prescribing drugs with generic names and, for patients’ point of view, the factor of cost-effectiveness. There is need of CMEs based on GCP and Standard Treatment Guidelines. Every institution must have Drugs and Therapeutic Committees.

Conclusion: For rational prescribing of drugs, there is a need of mass awareness amongst surgeons about good prescribing habit by following five steps of WHO Program on Rational Use of Drugs (RUD).

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Drug Prescribing Pattern in Surgical Wards of a Teaching Hospital in North India

Drug Prescribing Pattern in Surgical Wards of a Teaching Hospital in North India

Author(s): Salman MT, Akram MF, Rahman S, Khan FA, Haseen MA, Khan SW
Indian Journal for the Practising Doctor. Vol. 5, No. 2 (2008-05 - 2008-06)

ISSN : 0973-516X
Dr MT Salman, Dr SZ Rahman and Dr FA Khan are from the Department of Pharmacology; and Dr MA Haseen and Dr SW Khan from the Department of Surgery, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India – 202002.

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Abstract
Irrational use of medicines is widespread throughout the world. The main problems include the unnecessary prescription of drugs, particularly antimicrobials and injections. To investigate the situation in surgery wards, the present study was undertaken. Ninety six prescriptions were collected prospectively from post-operative patients admitted in surgery wards of the JN Medical College Hospital, AMU, Aligarh, and subjected for analysis according to the WHO/INRUD Indicators. VEN method was also applied to ascertain quality of drug procurement. It was revealed that the proportion of drugs from Essential Medicines List (EML) was 61.4%, while no drug was prescribed by generic name. Groups of drugs most commonly prescribed by general surgeons were antibiotics (93%), analgesics (60%), antacids (43%) and antiemetics (10%). The most extensively prescribed drugs from each of the above groups were injections Ceftriaxone and Amikacin, tablets Voveron, Pantoprazole and Metoclopromide, respectively. The average number of drugs prescribed per patient and cost per day per prescription was 4.8 and 246.1 INR, respectively. Average number of antibiotics prescribed per prescription was 2.2 and the average number of injections per prescriptions was 2.3. The results showed that the pattern of drug prescribing is not based on WHO criteria for rational use of drugs. The system is not at all evidence-based. It is thus necessary to make surgeons aware about good prescribing habit by following 5 steps of the WHO Program on Rational use of Drugs (RUD).