Effects of glycemic load on metabolic risk markers... [Am J Clin Nutr. 2010] - PubMed result

A recent study suggests that diet with a decreased Glycemic Load does not ameliorate metabolic risk markers such as fasting plasma glucose, insulin , serum total cholesterol , LDL-cholesterol , HDL-cholesterol ,triacylglycerol, high-sensitivity C-reactive protein, interleukin-6, tumor necrosis factor-alpha, monocyte chemoattractant protein and prothrombotic plasminogen activator inhibitor 1 in overweight subjects. This means that such subjects should concentrate on reducung weight and cholesterol rather than restricting sugar intake. Effects of glycemic load on metabolic risk markers... [Am J Clin Nutr. 2010] - PubMed result

Indian polypill study

The TIPS study was headed by Dr. Prem Pias Dean, SJMCH. Dr. Denis Xavier HOD, Dept of Pharmacology, SJMC And

Dr. Alben Sigamani Trial Manager Division of Clinical Trials St. Johns Research Institute Bangalore.

The concept of Polypill in Cardiovascular Diseases was by Dr. Salim Yusuf (Graduate from St. John's), Now the Director of PHRI Mc. Master university Canada.

The Study was funded by Cadila Pharmaceuticals.

The results of the study are published in Lancet Mar 30th 2009.

This team is now heading forward to conduct one more large clinical outcome based study with polypill, the clinical end points such as All cause mortality and CV mortality. This future study will answer the question such as.

1) Which particular patient can take the poly pill

2) Patient with certain risk factors needs to take which combination of Ploy pill. etc

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)60611-5/abstract

Indian scientists discover 'superpill' to combat heart disease Hindu - ‎Mar 31, 2009

'Polypill' could reduce heart disease, stroke: Researchers Calgary Herald

5-in-1 pill passes first major test Times of India

Five-in-one pill cuts heart attack risk Calcutta Telegraph