Thursday, March 12, 2009

New Pharmacological Drug Classes Introduced in 2008

Pharmacologic ClassFirst to be Marketed in the U.S.FDA Approved Indication11th Edition Reference
C1 inhibitor
C1 inhibitor (Cinryze)Routine prophylaxis against angioedema attacks in patients with hereditary angioedemapage 1405
CXCR4 chemokine receptor inhibitorplerixa (Mozobil)Mobilization of granulocyte-colony stimulating factor induced hematopoietic stem cells to the peripheral blood prior to collectionpage 1274
peripherally acting ยต-opioid receptor antagonistalvimopan (Entereg)Acceleration of the time to gastrointestinal recovery following bowel surgerypages 561-562
methylnaltrexone (Relistor)Treatment of opioid-induced constipation
thrombopoietin receptor agonisteltrombopag (Promacta)Treatment of thrombocytopenia in patients with chronic immune thrombocytopenic purpurapages 1441-1442
romiplostim (Nplate)

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