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Wednesday, September 16, 2009

Oral Insulin

1) The FDA has approved Oral-lyn, an insulin spray treatment for type I and type II diabetes, for its Investigational New Drug program.


The spray delivers prandial insulin orally through a device similar to an asthma inhaler, which sprays it on the inside of the cheek, rather than via injection.

Researchers have spent much time looking for alternative means of dispensing insulin to diabetics, and the IND program allows patients with serious or life-threatening conditions, and without suitable alternative treatment, to access drugs otherwise available only to those in a clinical trial.



2) Oramed has developed a tablet form of insulin in which the hormone's protein structure is supposedly protected by special adjuvants from destruction by gastric juice. The firm just reported positive results from a Phase 2A clinical trial with Type I diabetics.

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